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KMID : 0364219850280040237
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Korean Journal of Zoology
1985 Volume.28 No. 4 p.237 ~ p.244
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Protein Patterns of Blood Plasma in Pregnant Women by SDS/polyacrylamide Gel Electrophoresis
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Choi Won-Chul
Ha Man-Joon
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Abstract
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The plasma protein patterns of non-pregnant women, pregnant women, and normal male individuals were analyzed by SDS/polyacrylamide gel electrophresis. When the protein patterns of plasma of normal male individuals ranging from 10, 000 to 110, 000 daltons in molecular weights are compared to non-pregnant women, their protein patterns were the same. In this study, when the plasma of non-pregnant women are compared to pregnant women, no bands were occurred newly, but the quantity of some protein bands were increased or decreased during the pregnant periods. According to the results of measuring the molecular weights of the characteristic protein patterns, which are increasing or decreasing during the pregnancy as compared to the non-pregnant women, it was observed that the proteins over 76, 000 daltons in molecular weights were concerned in the facts mentioned above. That is, the protein of 86, 000 dalton in molecular weight was not increased in quantity until the second trimester of pregnancy, but was increased in the third trimester of pregnancy. The proteins of 91, 000-105, 000 daltons in molecular weights were gradually increased in accordance with the periods of pregnancy. On the contrary, the protein of 94, 000 dalton was rather decreased by the second trimester of pregnancy, but increased in the third trimester of pregancy. And the band of 99, 000 dalton was not changed in quantity significantly until the first trimester of pregnancy, but increased continuously from the second trimester of pregnancy to the third trimester of pregnancy. We tentatively suggest that the stages (the first, the second, and the third trimester) of pregnancy can be identified by the study on the protein patterns of the specific bands in the blood plasma of pregnant women.
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